Arginine Alpha-Ketoglutarate (AAKG) is a salt produced by combining two molecules of arginine to one molecule of alphaketoglutarate. Arginine is a substance that increases nitric oxide production therefore it is usually taken by athletes or body builders who undergo intense exercises and workouts to increase muscle mass and strength. On the other hand, alphaketoglutarate is a substance that plays a major role in amino acid metabolism and in harnessing energy.
The substances that make up AAKG are present in many foods, however AAKG compound is only found in the form of supplements. It must only be taken in 2 or 3 tablets, once or twice daily on an empty stomach, and is not recommended for continuous use for more than 60 days.
Benefits of AAKG
People who benefit much from AAKG supplements are body builders and athletes. AAKG is produced by the amino acid L-arginine that increases the production of nitric oxide (NO) in the body and it is believed that the presence of AAKG also causes the same effects thereby relaxing and enhancing the flow of blood to the muscles. It is important to remember though there are no scientific evidence that has been presented yet. However, a double-bind trial showed that it can improve some strength and power from weight training.
Several studies have shown that bodybuilders who used AAKG produced larger and longer lasting pumps. Their muscles were tighter and stronger. Taking in this supplement showed positive result in rapidly increasing strength, producing new muscle growth and accelerate recovery in the muscles. As a result, they acquired bigger muscles, stronger chest and broader shoulders.
It is also said that AAKG is taken to stimulate the immune system. The immunomodulatory properties found in AAKG can enhance host-defense mechanisms, particularly during injury and severe stress. In addition, AAKG is also taken by people who want to increase their sexual vigor. It has also been used in patients experiencing burns, surgery, and malnutrition. The intermediary metabolites of AAKG, which are glutamine and praline, may also contribute to promoting recovery from trauma.
There has been no significant report of side-effects for AAKG and no deficiency case has been reported either. Weight lifters who underwent double-bind trial for eight weeks have shown no changes in their heart and blood pressure. There were also no significant changes in their general and mental health. Some doctors believe that herpes patients should avoid supplements with arginine, for it may aid in the replication of the virus.