OLYMPUS UK YKAR1NE is an anabolic formulation containing (17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester, or YK-11, a compound structurally similar to DHT, commonly classified as SARM, compounds selectively activating androgen receptors.
There, AR-androgen complex combines with the required DNA fragments (androgen response elements – ARE) and recruiting appropriate regulators, ie. co-activators or co-repressors, it respectively intensifies, or inhibits, the transcription of genes enabling the development and rehabilitation of concrete structures.
The connection to the androgen receptors, there compete numerous compounds, including testosterone and dihydrotestosterone (DHT) – their excessive activity can lead to many adverse effects.
SARM term refers to a group of substances, both steroidal and non-steroidal, which as ligands of androgen receptors (AR) connected to the hormone-binding domains (LBD) they affect their functioning.
As a rule, they are not a substrate for 5a-reductase and aromatase, and thus they are not subject to changes to DHT and estrogens, and therefore, they are not associated with negative consequences of the activity of these hormones.
YK-11 irrespectively of a lack of possibilities to full activation of androgen receptors, it is able to increase the level of the main myogenic regulatory factors (MRFs), in particular: MyoD, Myf5 and myogenin, in a greater way than does it DHT. YK-11 enables a process of myogenesis mainly by increasing the concentration of follistatin (FST), through which it limits the activity of myostatin, a protein limitating muslce proliferation process over the naturally programmed size.
OLYMPUS UK YKAR1NE is an extremely powerful anabolic product, which mainly through increasing MRFs and blocking myostatin, it is capable of increasing the synthesis of new muscle fibers. By supporting the development of muscle mass, with concomitant loss of excessive body fat, it leads to an exposure of an extremely muscular and skimmed silhouette.
Olympus Labs Ykar1ne 90 Capsules | ||||||
Serving size: 1 capsule | ||||||
Servings per container: 90 | ||||||
Amount Per Serving | ||||||
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Other ingredients: Gelatin (Capsules) and Magnesium Stearate |