11-OXO is adrenosterone which is a hormone produced in the adrenal glands under the influence of adrenocorticotropic hormone (ACTH). 11-OXO works in two ways. First, it is a prohormone to 11-ketotesterone which is a non-aromatizing analog of testosterone. It shares many of testosterone’s benefits such as increased libido and increased muscle mass.
How 11-OXO works
11-OXO also works by selectively inhibiting the function of the 11beta-hydroxysteroid dehydrogenase type1 reductase (11HSD1R), an enzyme responsible for converting cortisone to cortisol in target tissues such as fat, liver, and muscle. 11-OXO simply occupies the enzyme, preventing cortisone from accessing it. This is known as competitive inhibition. If cortisone cannot access 11HSD1R then it won’t have the opportunity to be converted to cortisol at the target tissue. The nice thing about 11-OXO is that it selectively acts on the 11HSD1R enzyme. Thus, 11-OXO offers a method of controlling the negative actions of cortisol on the body without blocking cortisol’s vital functions necessary for life.
11-OXO useful only for cutting?
Cutting is its forte, however it is still very good for bulking. 11-OXO will help minimize fat deposition while on a hypercaloric diet.
Is 11-OXO suppressive?
11-OXOmay cause suppression at high doses due to the fact that it converts to 11-ketotestosterone, a potent androgen. This is exhibited especially at higher doses, 6+ caps/day. Always make sure to run the proper PCT after each cycle.
Is 11-OXO estrogenic?
11-OXOdoes not aromatize and it has a very low intrinsic estrogenic potential. In fact, in a study comparing it to 18 other common androgenic steroids it showed the lowest estrogenic potency (as measured through uterotrophic activity).
|Fusion Supplements 11-OXO 90 Capsules|
|Serving Size: 1 Capsule|
|Servings Per Container: 90|
|Amount Per Serving|
|Other Ingredients: Microcrystalline Cellulose, Gelatin, Rice Flour, Magnesium Stearate|