The popularity of joint support products lies in their double effect. They can both ease joint pain and treat damaged joints. They can be used both for prevention and treatment. These products strengthen connective tissues, thus they keep the joints healthy. They provide tendons and ligaments with proper elasticity, so those can efficiently weaken shake and strain caused by intensive workout and repeated exercises.
Glucosamine can play a role in sustaining the structure and function of cartilage found in joints. It possibly has an anti-inflammatory effect, too. It is used in therapies of arthrosis and it helps prevent and treat osteoarthritis. It supports cartilage in a way that every single glucosamine helps fill the cartilage with water by binding three water molecules. This is essential, because cartilage does not contain blood vessels so its cells can only get nutriment via water-rich tissues. Glucosamine from an external source makes up the deficiency, supports preteoglycan synthesis and thus slows down or even stops harmful processes in the body of patients with arthrosis. Studies revealed that glucosamine and chondroitin sulfate mutually enhance each other’s effect. Consequently, it is recommended to take 250-300 mg chondroitin three times a day beside glucosamine.
RDA- Manufacturers’ dosing recommendation: daily 3x500mg
Chondroitin sulfate is the component of cartilage in animals. Studies revealed that glucosamine and chondroitin sulfate mutually enhance each other’s effect. Consequently, it is recommended to take 250-300 mg chondroitin three times a day beside glucosamine.
RDA:- Manufacturers’ dosing recommendation: daily 3x500mg
It is widely accepted that MSM is a relief of joint pain. It is an organosulfur compound; our body uses it for making enzymes, antibodies (immunoglobulins), glutathione, connective tissues, and mucous membranes. It is a safe antioxidant; it has anti-inflammatory and detoxifying effects. It is often used as a component of joint support formulas.
RDA:- Manufacturers’ dosing recommendation: daily 100-300mg
Collagen is a protein which is the main component of connective tissue. It is the most abundant protein in mammals, because it makes up 25% to 30% of the whole body protein content. It can be found in skin, tendons, cartilages, bones, connective tissues, organs, and it also makes up 1-2% of muscle tissue. Gelatin, which is used in food industry, is made by the hydrolysis of collagen. Collagen is widely used in cosmetic surgery e.g. for burn patients, for reconstruction of bone, and for dental, orthopedic, and surgical purposes. According to some clinical studies, hydrolyzed collagen plays an important role in the management of osteoarthritis, because it has a role in the synthesis of cartilage matrix due to its amino acid content.
Eggshell membranes are natural sources of glucosamine, chondroitin, and hyaluronan. The eggshell membrane’s structure is made up of thin protein layers which are connected like a web. Protein fibers contain keratin – which is relatively high in sulfur – and collagen, and they are surrounded by mucopolysaccharide material (containing hyaluronan, chondroitin sulfate, and glucosamine).